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Importantly, elimination of this radiation-induced G2/M blockade is a promising radiosensitising approach as cancer cells frequently have a deficient G1 checkpoint (60, 61)

Reported effects may include: Mild bloating or stomach discomfort Nausea Headache Skin rash Unpleasant taste (with sublingual use) Stop the medication and contact your provider promptly if you develop: Persistent abdominal pain or vomiting Wheezing or shortness of breath Severe rash or swelling Any unusual or worsening symptoms Trouble breathing Swelling of face, lips, or tongue Severe allergic reaction Chest pain, severe dizziness, or fainting Take exactly as prescribed

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TTs concentration was meaningfully decreased in GO (16%), GO + aminoguanidine (11%), and GO + NAC (15%) in comparison with BSA (Fig